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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0743276182e5bbd73d110ea96e8ead8b4f46eb429f4bc34e97e5e719739119bc' 
  AND token = 'UtowEbYZWIT2N5032sbHgGkSaPe0Tl6/AkaZpCsuwbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}