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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb63aeadaa73f6b7643e05f9d2d599124377c536d39c861ab2ba195cf5633f03' 
  AND token = 'dQ+0L7eY0vbUNhAlPoNhwxByUS1oL0pE9OX552b/lN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}