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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53fa42227a8c29a9fd10113cc50dbdb6b6871967182f99c9f002dd19eaaf20a5' 
  AND token = 'Nqqpk9e0EE4oOQQ2vw/+bN3phHZa1G9UKrU7gHAGlZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}