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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f342b1ed8d4a05e4196e8625ee0306172e4285ba62e8fc25f43838fbbb108cdf' 
  AND token = 'ST7p4gIOT/Q0vMORHtpC2IpAATeWvuhTEqtyxYvNxNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}