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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3e3acab1958f3e40e2b99242d407e3685a56f68f49a908d767a8c70c5acda50' 
  AND token = 'vIS1LRWzpdz2aAewhG9dnmJZmpsb3vSDnQ60BJ+N5HE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}