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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a73076b0bed39bdd57dcec7b24396c96533946c4e8568701fcc46e42ad079b5f' 
  AND token = 'Lcfz+mQe+jgjbQWj4aUkirfB3GODWKI2Ya9JI2skx0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}