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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee8d255110108319fd3797c07aedfb59e8d13ce1a799881e7c5fb72949ab811f' 
  AND token = 'pTeKs6SQ2LVhOcVxiaprOo6leSE59z2tM7l//AEj1Qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}