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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57d346524e5d4cb544fca20bb11f46d56344bd04a9176b9da46aef7dcf92debe' 
  AND token = '10W7igH2QZz5NvFLzVsopwr5b4Fn2KqDtudvhSi9PTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}