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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8494a9b08777698b93a5f37cf7ba5d3bcb04e6fa72914ce5fa6f6486da5f1c69' 
  AND token = 'dKHd5IfUH1Mroeb5EgpYCw0rK7nKDvG3mJb1Rhp5aOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}