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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0ea9c0e2003c97949ff8c1c4f71ad9780f914bd37de423e845966816691b96d' 
  AND token = 'drmO8wI/xOeaRF5W4ce9IGA0R3/hwM9JOxOqnNbFgDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}