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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec476d9b3695944086f9dac4f88d0059ac06595de4d37797cb2e010c57853fd4' 
  AND token = 'N/7amdtP2XLATx5zOThEXLii6np/q4ssa4CqlWWGyU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}