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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd12e63ec29a35d42c505dd06ec69c6459db72e127d47a5ba238b192a8bddd021' 
  AND token = '8OMakEZUv38Ywi2LsgKa1kS1kLojUlCYlYjVDzv+jZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}