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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59502b497af53249637f1d67ad6e7bb5c8f67bafc9a7693b3e25afdd0997c5cc' 
  AND token = 'cqqSaPniV9F1jnPzxIBccvHmLd6Pd2jaWAagSn/z5To=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}