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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '015d9697910ad1e5669b2ddad4b302f29bf0cbf1f714712a954885a1a2b95b57' 
  AND token = 'F+CLivE1ipRya8Y0XArJMa8WaAun7gIkcFznxjqQZuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}