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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ab33b1e03e4c147b6494da03d988358da856617ebdca064e19410f8bbf8057d' 
  AND token = 'AJlYQp5Vma7lpotXHXwAGbBwgNMrWAT+je7IJWpB2Ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}