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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8efdd3e5bc776365ba411071f0b1279f4a4644507ae6b3e745b3bb9b047159a' 
  AND token = '33VaAwlY5+Bpbi+jbEIlhbznh5dTX46907Sku7ScBAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}