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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59982d2c45f2b1fc9e0fb548f349a5e23635a10145086a4b880a8db36a01900f' 
  AND token = 'rFFK3mhXAZBeMqAk93rExh+t5LGivGloQopwreImJ6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}