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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39875d1efb6610cb5bf8355de5c14fcb59107df955116b07d58c90c83397104c' 
  AND token = 'T1OGpJzcPIYW49NxB2MGV2a9gqb+vpER3XVeNe7EZu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}