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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f6cc7254e6451f1b38fe1a013712e731feee04321f0bc649da20aa74655990d' 
  AND token = 'fY9C2eoNHdsyEVH6IHlLWIDFNQ3bkRvogC6QkzjG9Mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}