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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1efe3e0f21f1744cd4e7770679cc253a76431e4b4c3b36b7bad537813ea966f2' 
  AND token = '1weZBjZsNyA0EcmDPFcU7im0WKy/bbA+bnBbygPYmYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}