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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3cc36947f545af5878c3199f39e519c639c6f7215212844f8f2721aa1d67147' 
  AND token = 'NC6Ft0kNMR732FVvb6OAwr7BgTeJccT6JD6JoTX+XMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}