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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2201395ac9ffbd310c722827f22651674dc71ab4a9353184f7d0f0329d612b86' 
  AND token = 'xl2kpKb/KZy0bOuQyTHLsExy8yb5afc6lQF5rNl3NVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}