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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b22c1ea97d2c97febaa47f8deedb0d5a376e8f7213108fb648518b409d0092b' 
  AND token = '1MVW5WOUL8rv1Q4jmTs/ZSyLCJ7YWpzFaVySRsehdmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}