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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04b0c0728cd4a6650572f99d35266c6975dd70d28d07747511d54edb335460b0' 
  AND token = '9ZlYH/h1YsKWL86jpoh5xC+HXLKHVrES1dnVD7dsXfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}