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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8011d6c964894b880325b24255aead282a359a02b996f8fd5229cb6aadcd9721' 
  AND token = 'U8q19k8+WAHwGCqUyQVugZFp5aLmyRqcyCl8zBWlHUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}