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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fec18a0b3d679ca426b79bb8bdc0501e28691bf52bbef1802b1e00644d450bb' 
  AND token = '5l8I3CiY6OaoNbFo1nVNh4dqHgRePGBPkIBW2f+NRWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}