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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bee6b868ab50803fa398b3ea9e565d03fcd9d6f02506016551ff499e346cdce6' 
  AND token = 'V4Sis1050ARcmTUaH7o6qc9Re5ZEP0LCSozqM/PbxUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}