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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f879cb23790bc19fdfbd33357729af8b4ace66a655078ba39e942801fb8a55f' 
  AND token = '8DSZ3+9olV6z3Hx7EKpCscgrKoRO3Cxsr4oBYnQ7vfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}