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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a1f1ce8be0279239d788a7768ac7b122af2e3619ec0dd45af7e7ff4f53222a' 
  AND token = 'TXjKxG+/RPm8zgZca0+X0TENNQtPRPYb5S7vcRv/R/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}