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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '099bf3d2b284e06a3bbb7c7e2792c8f191d992dcf61726ccaf4c04f09c8969c4' 
  AND token = 'VDx44N3UVhEwzPPDg6/bFf9F8ytPzc4FpKNwGIAWjCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}