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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd10d61b0065077e8320643b3ac674f2705e41b3a220918df316eac3bf27da3a5' 
  AND token = 'pfdHAoBfRzc51r6DSLRm0+pWjeLXlrdGTqWABB+4qhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}