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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46780e93e4390bc6d1140c50e0da2170615cba10ab11de6401ea6770b93149a8' 
  AND token = 'GRgFudtoBrsr46iD44xN7Q4o00XU3QWorkCcXKywPqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}