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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d77a9a6c91732440a7b4527e774fe49bd8f64fb4ab0ead18ea61c712c30b234' 
  AND token = 'RT1zmclL1vQsyL3K+apAQj0jZAy3yEMffIn3t5fhjwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}