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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ea18bcf478222072ee712cc6ece1cc100ca2a213c57b306f8b4ee771d72b574' 
  AND token = 'fuK1/ZKum0C125Mbh46JTro8nHaTZBJiTH39ryx2fLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}