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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5900ff054ac7d9bed7926c7cb721a65f29c8580d043e8df140ec926c6edb554a' 
  AND token = 'h84KhDvZB+Qv6Cwyuk4a1uxQamBBY4t+4kgobAAKBDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}