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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21fedbf58f41a2d9480f1523869f661fd9636fd032cf2539dec4d1b8bfe105b9' 
  AND token = 'cuukDcOIoERZP5ZtBi8jvj98dnrVD1GTrglugK/zfWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}