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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c127fd5e114451c8aa7b53b6bfcd463404d74dd3071c08a544dfb479162d3a08' 
  AND token = 'Rx0pekQS3mlpjmpEnmMYKVrRLYH+1zT0reRfbxkCYhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}