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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af3c08b3fdbfb1e800521e7019d6243af7f6beaf932ee6f30138f4d338f5b3e9' 
  AND token = 'shYPK/BVYaQGqgTbBmod8APJDRdoGRo9ZyKsyqMEUAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}