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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fc035ce7176730b572d18aa7ca39b7267e7f072fa98493d154be36a5c5e3016' 
  AND token = '/wDTRwRsRrnLTO0QuySvbMT1zYxEoBgZ3RFZ04JlQNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}