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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '657d56ec8b4acc8ad900113db1a9a71d101169456699c56857ba96196815001b' 
  AND token = 'uxFQvKYvLpsXMnk+IAH5hdLRMpPYtaHhLyFqj1szBDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}