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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64778692f81dd2d303ad6f2c4e6dda9d630a359fa69744cc58837a9e719becee' 
  AND token = 'PxtDGNyukS9qpUjWsp+24UWnZjNOWPAhkzV0KmzaL94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}