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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9329d32dc19cf17e3386ef64a4e957e32057a99cf1a43a9396051e530c37aaef' 
  AND token = '79skKGkE4t6muukT9imUDwDcg7VxczuoAIfnNOHwSA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}