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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e29f7e3ad976fe84ba82cc8b01cb2ecc710dc8d3a0465715798d0045372b7bb2' 
  AND token = 'Fl4Z0UjdERMm+uMhXSvDiRseXRCpjQAoM4Tw15WC7wY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}