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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c6706f1d8cefd2f05eea0ec5e1de19296280e6d1391378e9a22f51f2b6e310c' 
  AND token = 'TWWCT8DMFSnCNDNXd/ywRI4q31a/cSX/u4dh+RIQ4CA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}