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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28100ffff3bb1d7326d054e8f47d4001a0fb9d940c4e569b137a2a465588307d' 
  AND token = 'SzbN475CzulXt2omvdtdHCft3NGgoMbxqVrDruYY0UU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}