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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5d9c892ff7f3e1f1b34c8750f0baeafde8e060ec25b459050b65b5f5f6e586c' 
  AND token = 'H/spSoNBDGOQS3ml4Xsub75YzWtEe5kyxQgxsdLxDFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}