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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50a435a5cb813eff1f9f487004fe3866aeb93639a368bc8737592a270e4e4c3' 
  AND token = 'fwabVjMxS9vEe4D8aXoDRSKIVc/K2kBicHisi/YosCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}