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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d0bb268cc48b744c492b853eef444aa6776f8cf32abf2277bdb68eb2edefa07' 
  AND token = '6r1iNgyDf5PxKZhk/ODKO0i7C2xWtfmwN6grxq4yCDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}