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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e20d367bf635dc4061fbfd2e7f4310a1ead28e534654e57c14803ce929ef286' 
  AND token = 'APCnFcp8L/Novoc0/5Gn6m+CCfKDT6us+5R8+f0Tvws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}