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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d7d45a8b9f741b224d4a92f91de3038a31e12e4a4270962ef2a510dfe32ed64' 
  AND token = 'N9gMI/hKqZVVDUa4yg3Myf8BwV6V0+0GdaW5XB93nM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}